Education
- BSc with distinction: cum laude, awarded by University College Utrecht, an honours college of Utrecht University in 2018.
Science major, completed Cognitive Neuroscience, Chemistry, Molecular Cell Biology, and Medicine tracks. Gained the ‘Pre-Med’ qualification recognised by research medical doctor master programmes in the Netherlands.
- MSc with distinction: cum laude, awarded by the Molecular Biosciences programme at Heidelberg University in 2021.
Focused in Bioinformatics and Computational Biology.
- PhD degree in Bioinformatics and Systems Biology awarded by PSL University, with the speciality in Informatics, the 4th of June, 2025.
Project focused on the development and application of image-processing workflows for characterising membrane morphologies and resolving membrane protein molecular structures from cryo-electron tomography data.
Funded by the EuReCa international PhD programme supported by the European Union’s Horizon 2020 research and innovation programme, Marie Skłodowska-Curie Actions fellow.
Member of l’école doctorale Complexité du Vivant, Sorbonne University.
Research experience
- 09 2021 - 06 2025: PhD project
- The Physical Chemistry Curie Lab (UMR168), Institut Curie
- The development and application of image-processing workflows for characterising membrane morphologies and resolving membrane protein molecular structures from cryo-electron tomography data.
- Thesis title: Automated Image Processing of Membranes and Membrane Proteins in Cryo-Electron Tomography
- Speciality: Informatics
- Hosted by the Molecular Microscopy of Membranes team led by Dr. Daniel Lévy
- Supervised by Dr. Daniel Lévy & Dr. Manuela Dezi
- Thesis committee members: Prof. Simon Anders, Dr. Mickael Cohen, & Dr. Slavica Jonic
- Jury members: Prof. José María Carazo & Dr. Irina Gutsche as reviewers, Dr. Charles Kervrann as president of the jury/the representative examiner of PSL University, Prof. Daniel Castaño Díez & Dr. Emmanuelle Quemin as external examiners.
- 03 2020 - 08 2021: Master thesis
- The Structural and Computational Biology unit, the European Molecular Biology Laboratory (EMBL) Heidelberg
- The development of an image processing pipeline for resolving structures of the Mumps viral capsid in the cellular context by means of in situ cryo-electron tomography.
- Hosted by the Mahamid group led by Dr. Julia Mahamid
- Supervised by Dr. Xiaojie Zhang & Dr. Julia Mahamid
- Examiners: Prof. Rebecca Wade & Prof. Georg Stoecklin
- Publication: Molecular mechanisms of stress-induced reactivation in mumps virus condensates.
- 01 - 02 2020: Internship
- Heidelberg Institute for Theoretical Studies
- Evaluation, improvement and benchmarking of the novel drug-target residence time (τ) estimating molecular dynamics sampling computational method: τ-random acceleration molecular dynamics (τRAMD), used for the ranking of drug candidates according to their τ and gaining insights into ligand-target dissociation mechanisms.
- Hosted by the Molecular and Cellular Modelling group led by Prof. Rebecca Wade
- Supervised by Dr. Daria Kokh
- Publication: A workflow for exploring ligand dissociation from a macromolecule: Efficient random acceleration molecular dynamics simulation and interaction fingerprint analysis of ligand trajectories.
- 09 - 12 2019: Internship
- Centre for Molecular Biology Heidelberg (ZMBH)
- Single-cell transcriptomics-based study of the interaction between Sertoli cell and cells of spermatogenesis in the fast-evolving testis across human and animal species. Mentored by Dr. Simon Anders on the development of a novel method for continuous classification of single cells.
- Hosted by the Kaessmann group led by Prof. Henrik Kaessmann
- Supervised by Dr. Florent Murat
- 04 - 08 2019: Internship
- German Cancer Research Centre (DKFZ)
- Electron spray ionisation mass spectrometry-based characterization of proteins in the polycomb repressive complex 2 (PRC2, a key epigenetic regulator for normal development and various diseases) and investigation of their recruitment in cancer.
- Hosted by the Division of Proteomics of Stem Cells and Cancer led by Prof. Jeroen Krijgsveld
- Supervised by Dr. Dimitris Papageorgiou
- 02 - 03 2019: Internship
- Max Planck Institute for Medical Research
- Giant unilamellar vesicle-based microfluidics fabrication of uniform human neural co-culture spheroids for high-throughput microplastic neurotoxicity screening, original and independent research project.
- Hosted by the Department of Cellular Biophysics led by Prof. Joachim Spatz
- Supervised by PhD candidate Oskar Staufer
- 10 2017 - 08 2018: Bachelor thesis
- Hubrecht Institute
- Projects: 1) Induction of the differentiation of gastric endocrine and exocrine cells in human stomach organoids, 2) and Epstein-Barr virus-positive gastric adenocarcinoma modelling with human stomach organoids using genome editing strategies (CRISPR/Cas9 and lentivirus infection).
- Hosted by the Clevers group led by Prof. Hans Clevers
- Supervised by Dr. Georg Busslinger
- Examiner: Dr. Bas Defize
- 07 - 09 2017: Internship
- Regenerative Medicine Centre Utrecht, University Medical Centre Utrecht
- Introduced to cell/tissue culture, and confocal imaging with fluorescence-stained hydrogel-based 3D tissue culture for the development of heart-on-a-chip used to investigate patient-specific cardiac remodelling following myocardial infarction. Literature study on the use of nanoparticles for cardiac repair. Selected through the University College Utrecht Alumni Internship program.
- Supervised by Dr. Tom Bracco Gartner & Dr. Jesper Hjortnaes